I'm also getting this error. The game was working perfectly fine for six straight hours on a fresh install, and now suddenly it seems to happen about 6-7 minutes into playing almost consistently, and even more consistently whenever I ride through a bush. I have ZERO idea what changed, and the only mods I have installed are all relatively light and have no known conflicts... Not that it matters since deleting them one at a time changed NOTHING.
The only thing I can figure is that it's somehow the fault of Rampage Trainer, since initially when I installed that mod and used it just to give myself the Ultimate Edition content, the older saves I had would immediately hard crash the game upon trying to load them manually; No error code, just straight to desktop. Only the most recent saves would work every single time.
Doing a fresh install of the game right now to see if that somehow helps, guess I'll get back with info on that soon