I didn't manage to get Lenny's Simple Trainer to work on Linux, but I finally got Script Hook working for RDR2 on Linux. I used these Launch options in Steam WINEDLLOVERRIDES=dinput8,ScriptHookRDR2,dxgi=n,b PULSE_LATENCY_MSEC=60 %command% -adapter 1 -vulkan -width 1920 -height 1080 -USEALLAVAILABLECORES -cpuLoadRebalancing -ignorepipelinecache Keep in mind that I have an AMD card, so If you have an Nvidia card, just go to protondb and find the Nvidia equivalent to my Launch options. The line "WINEDLLOVERRIDES="dinput8=n,b"" is what allows Script Hook to load. So without it, Native Trainer won't load when you press F5.